Chlorhexidine Gluconate (CHG) solution is a broad-spectrum antimicrobial agent widely used for skin disinfection, surgical scrubs, wound cleansing, and oral rinses. It works by disrupting the cell membranes of bacteria, fungi, and some viruses, making it highly effective in reducing infection risks in medical and dental settings. Available in various concentrations, typically ranging from 0.05% to 4%, CHG is commonly used in preoperative skin preparation, catheter site cleaning, and hand hygiene for healthcare workers. Its ability to provide prolonged antimicrobial activity, often lasting for hours after application, makes it a preferred choice for infection control in hospitals and clinics.

In addition to medical applications, Chlorhexidine Gluconate solution is also used in dental care for treating gingivitis and reducing oral bacterial load. However, it should be used as directed because improper or prolonged use may lead to side effects like skin irritation, allergic reactions, or staining of teeth and dental restorations in oral formulations. CHG should not be used in the eyes, ears, or deep wounds, as it may cause severe irritation or toxicity. Its strong and lasting antiseptic properties, combined with its versatility, have made Chlorhexidine Gluconate a critical component of infection prevention protocols in healthcare and personal care worldwide.

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